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Sivelestat Sodium Hydrate

Tier C — Watch / trade

Sivelestat Sodium Hydrate

-
Originator
2002
First approval
-
Expiry (public)
$0.06B ▲
Peak sales
Small molecule
Type

Targets:ELANE

Brand:Elaspol

Indications (approved):Acute lung injury, 全身炎症反应综合征

Regional status

US
No progress
2001-08-01
EU
Phase II
2001-08-01
China
Approved
2020-03-11
Japan
Approved
2002-04-11

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 7 · Total yield 8.55 g
SIVE-001610-14-0SIVE-00280299-93-0SIVE-003150374-96-2SIVE-004150374-97-3SIVE-005150374-99-5SIVE-006150374-98-4SIVE-007127373-66-4SIVE-00898-67-9SIVE-0093282-30-2SIVE-010188114-91-2API · Sivelestat Sodium Hydrate
CodeCAS No.Intermediate
SIVE-001610-14-02-nitrobenzoyl chloride
SIVE-00280299-93-0benzyl glycinate 4-methylbenzenesulfonate
SIVE-003150374-96-2benzyl (2-nitrobenzoyl)glycinate
SIVE-004150374-97-3benzyl (2-aminobenzoyl)glycinate
SIVE-005150374-99-54-(chlorosulfonyl)phenyl pivalate
SIVE-006150374-98-44-(N-(2-((2-(benzyloxy)-2-oxoethyl)carbamoyl)phenyl)sulfamoyl)phenyl pivalate
SIVE-007127373-66-4(2-((4-(pivaloyloxy)phenyl)sulfonamido)benzoyl)glycine
SIVE-00898-67-94-hydroxybenzenesulfonic acid
SIVE-0093282-30-2pivaloyl chloride
SIVE-010188114-91-2sodium 4-(pivaloyloxy)benzenesulfonate

Frequently asked questions

What are the approved indications of Sivelestat Sodium Hydrate?

Approved indications include: Acute lung injury, 全身炎症反应综合征.

When does the Sivelestat Sodium Hydrate patent expire?

No public expiry year is available for Sivelestat Sodium Hydrate yet; this page updates once verified.

How many synthesis routes are recorded for Sivelestat Sodium Hydrate?

1 synthesis routes are recorded; the shortest is 7 steps with 8.55 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Sivelestat Sodium Hydrate intermediates?

All intermediates in Sivelestat Sodium Hydrate routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Sivelestat Sodium Hydrate intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-27