普拉睾酮
Tier C — Watch / tradePrasterone
Targets：AR、ERs
Brand：Intrarosa、茵若飒
Indications (approved)：外阴阴道萎缩、萎缩、性交困难
Regional status
Synthetic routes & intermediates4 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| PRAS-001 | 57-88-5 | (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol |
| PRAS-002 | 604-35-3 | (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate |
| PRAS-003 | 514-50-1 | (3S,5R,6R,8S,9S,10R,13R,14S,17R)-5,6-dibromo-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate |
| PRAS-004 | 53274-78-5 | (3S,5R,6R,8S,9S,10R,13S,14S)-5,6-dibromo-10,13-dimethyl-17-oxohexadecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate |
| PRAS-005 | 563-41-7 | hydrazinecarboxamide hydrochloride |
| PRAS-006 | 563-41-7 | hydrazinecarboxamide hydrochloride |
| PRAS-007 | 63-05-8 | (8R,9S,10R,13S,14S)-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione |
| Code | CAS No. | Intermediate |
|---|---|---|
| PRAS-008 | 63-05-8 | (8R,9S,10R,13S,14S)-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione |
| PRAS-009 | 571-36-8 | (8R,9S,10R,13S,14S)-10,13-dimethyl-1,4,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione |
| PRAS-012 | 4968-05-2 | (8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate |
| PRAS-013 | 70226-84-5 | (8R,9S,10R,13S,14S)-10,13-dimethyl-1,2,7,8,9,10,11,12,13,14,15,16-dodecahydrospiro[cyclopenta[a]phenanthrene-17,2'-[1,3]dioxolan]-3-yl acetate |
| PRAS-014 | 7745-40-6 | (3S,8R,9S,10R,13S,14S)-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydrospiro[cyclopenta[a]phenanthrene-17,2'-[1,3]dioxolan]-3-ol |
| Code | CAS No. | Intermediate |
|---|---|---|
| PRAS-005 | 563-41-7 | hydrazinecarboxamide hydrochloride |
| PRAS-010 | 979-02-2 | (3S,8R,9S,10R,13S,14S)-17-acetyl-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate |
| PRAS-011 | 4968-05-2 | (8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate |
| Code | CAS No. | Intermediate |
|---|---|---|
| PRAS-008 | 63-05-8 | (8R,9S,10R,13S,14S)-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione |
Frequently asked questions
What are the approved indications of Prasterone?
Approved indications include: 外阴阴道萎缩, 萎缩, 性交困难.
When does the Prasterone patent expire?
No public expiry year is available for Prasterone yet; this page updates once verified.
How many synthesis routes are recorded for Prasterone?
4 synthesis routes are recorded; the shortest is 2 steps with 0.35 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Prasterone intermediates?
All intermediates in Prasterone routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Prasterone intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24