马来酸茚达特罗
Tier C — Watch / tradeIndacaterol Maleate
Targets：ADRB2
Brand：Arcapta、Onbrez/Arcapta、昂润、Hirobriz、Onbrez
Indications (approved)：慢性阻塞性肺疾病
Regional status
Synthetic routes & intermediates3 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| INDA-001 | 63404-86-4Available | 8-(benzyloxy)-5-(2-chloroacetyl)quinolin-2(1H)-one |
| INDA-002 | 172967-64-5Available | (R)-8-(benzyloxy)-5-(2-chloro-1-hydroxyethyl)quinolin-2(1H)-one |
| INDA-003 | 173140-90-4Available | (R)-8-(benzyloxy)-5-(oxiran-2-yl)quinolin-2(1H)-one |
| INDA-004 | 312753-70-1Available | 5,6-diethyl-2,3-dihydro-1H-inden-2-amine |
| INDA-005 | 753498-24-7Available | (R)-8-(benzyloxy)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-2(1H)-one benzoate |
| INDA-006 | 135-01-3Available | 1,2-diethylbenzene |
| INDA-007 | 625-36-5Available | 3-chloropropanoyl chloride |
| INDA-008 | 312753-50-7Available | 3-chloro-1-(3,4-diethylphenyl)propan-1-one |
| INDA-009 | 312753-51-8Available | 5,6-diethyl-2,3-dihydro-1H-inden-1-one |
| INDA-010 | 312753-52-9Available | (Z)-5,6-diethyl-2-(hydroxyimino)-2,3-dihydro-1H-inden-1-one |
| Code | CAS No. | Intermediate |
|---|---|---|
| INDA-004 | 312753-70-1Available | 5,6-diethyl-2,3-dihydro-1H-inden-2-amine |
| INDA-011 | 530084-79-8Available | (R)-8-(benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one |
| INDA-012 | 1585234-56-5Available | 8-(benzyloxy)-5-((1R)-2-bromo-1-(1-butoxyethoxy)ethyl)quinolin-2(1H)-one |
| INDA-013 | 1585234-59-8Available | 8-(benzyloxy)-5-((1R)-1-(1-butoxyethoxy)-2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)ethyl)quinolin-2(1H)-one |
| INDA-014 | 753498-33-8Available | (R)-8-(benzyloxy)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-2(1H)-one (2R,3R)-2,3-dihydroxysuccinate |
| Code | CAS No. | Intermediate |
|---|---|---|
| INDA-018 | 62978-73-8Available | 5-acetyl-8-hydroxyquinolin-2(1H)-one |
| INDA-019 | 93609-84-8Available | 5-acetyl-8-(benzyloxy)quinolin-2(1H)-one |
| INDA-020 | 100331-91-7Available | 8-(benzyloxy)-5-(2,2-dihydroxyacetyl)quinolin-2(1H)-one |
| INDA-021 | 1534357-84-0Available | 8-(benzyloxy)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-2(1H)-one |
| INDA-022 | 312753-33-6Available | 5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one |
| INDA-004 | 312753-70-1Available | 5,6-diethyl-2,3-dihydro-1H-inden-2-amine |
| INDA-015 | 1127-45-3Available | 8-hydroxyquinoline 1-oxide |
| INDA-016 | 15450-72-3Available | 2-oxo-1,2-dihydroquinolin-8-yl acetate |
| INDA-017 | - | 5-acetyl-2-oxo-1,2-dihydroquinolin-8-yl acetate |
Frequently asked questions
What are the approved indications of Indacaterol Maleate?
Approved indications include: 慢性阻塞性肺疾病.
When does the Indacaterol Maleate patent expire?
No public expiry year is available for Indacaterol Maleate yet; this page updates once verified.
How many synthesis routes are recorded for Indacaterol Maleate?
3 synthesis routes are recorded; the shortest is 5 steps with 18 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Indacaterol Maleate intermediates?
21 intermediate CAS of Indacaterol Maleate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Indacaterol Maleate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24