硫酸氢司美替尼
Tier C — Watch / tradeSelumetinib sulfate · all drugs expiring in 2032 →
Targets：MEK2、MEK1
Brand：科赛优、Koselugo
Indications (approved)：丛状神经纤维瘤、神经纤维瘤病I型
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| SELT-001 | 61079-72-9 | 2,3,4-trifluorobenzoic acid |
| SELT-002 | 197520-71-1 | 2,3,4-trifluoro-5-nitrobenzoic acid |
| SELT-003 | 284030-57-5 | 4-amino-2,3-difluoro-5-nitrobenzoic acid |
| SELT-004 | 284030-58-6 | methyl 4-amino-2,3-difluoro-5-nitrobenzoate |
| SELT-005 | 62-53-3 | aniline |
| SELT-006 | 606093-58-7 | - |
| SELT-007 | 606093-59-8 | - |
| SELT-008 | 606143-93-5 | - |
| SELT-009 | 606143-46-8 | - |
| SELT-010 | 606144-02-9 | - |
| SELT-011 | 606144-04-1 | - |
| SELT-012 | 391212-29-6 | methyl 2-((2-fluoro-4-iodophenyl)amino)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxylate |
| SELT-013 | 606144-05-2 | - |
Frequently asked questions
What are the approved indications of Selumetinib sulfate?
Approved indications include: 丛状神经纤维瘤, 神经纤维瘤病I型.
When does the Selumetinib sulfate patent expire?
Based on public sources, the Selumetinib sulfate patent expires in 2032.
How many synthesis routes are recorded for Selumetinib sulfate?
1 synthesis routes are recorded; the shortest is 11 steps with 2.11 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Selumetinib sulfate intermediates?
All intermediates in Selumetinib sulfate routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Selumetinib sulfate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24