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Tier C — Watch / trade

Macimorelin Acetate

COSCIENS Biopharma Inc
Originator
2017
First approval
-
Expiry (public)
No sales data
Peak sales
化学药
Type

TargetsGHSR

BrandMacrilen、Ghryvelin、Solorel

Indications (approved)生长激素缺乏

Regional status

US
临床二期
2012-05-01
EU
批准上市
2019-11-01
China
-
Japan
-

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 6 · Total yield 2.07 g
Synthetic routes & intermediates Route 1
CodeCAS No.Intermediate
MACIM-0017432-21-5(S)-2-(((benzyloxy)carbonyl)amino)-3-(1H-indol-3-yl)propanoic acid
MACIM-00220696-64-4(S)-benzyl (1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)carbamate
MACIM-00320696-57-5(S)-2-amino-3-(1H-indol-3-yl)propanamide
MACIM-004381231-54-5tert-butyl ((R)-1-(((R)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)carbamate
MACIM-005381231-55-6tert-butyl 3-((R)-3-amino-2-((R)-3-(1-(tert-butoxycarbonyl)-1H-indol-3-yl)-2-((tert-butoxycarbonyl)amino)propanamido)-3-oxopropyl)-1H-indole-1-carboxylate
MACIM-006381231-56-7tert-butyl 3-((R)-2-amino-2-((R)-3-(1-(tert-butoxycarbonyl)-1H-indol-3-yl)-2-((tert-butoxycarbonyl)amino)propanamido)ethyl)-1H-indole-1-carboxylate

Frequently asked questions

What are the approved indications of Macimorelin Acetate?

Approved indications include: 生长激素缺乏.

When does the Macimorelin Acetate patent expire?

No public expiry year is available for Macimorelin Acetate yet; this page updates once verified.

How many synthesis routes are recorded for Macimorelin Acetate?

1 synthesis routes are recorded; the shortest is 6 steps with 2.07 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Macimorelin Acetate intermediates?

All intermediates in Macimorelin Acetate routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Macimorelin Acetate intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-24