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地拉罗司

Tier B — Position early

Deferasirox

诺华制药
Originator
2005
First approval
-
Expiry (public)
$1.1B ▲
Peak sales
化学药
Type

TargetsNot applicable

BrandExjade、Jadenu、Exjade/Jadenu、恩瑞格

Indications (approved)地中海贫血、铁超负荷、β-地中海贫血

Regional status

US
批准上市
2005-11-02
EU
批准上市
2006-08-28
China
批准上市
2010-06-12
Japan
批准上市
2008-04-16

Synthetic routes & intermediates2 routes

Originator routes × 1Optimised (non-patent) × 1Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 2 · Total yield /
Synthetic routes & intermediates Route 1
CodeCAS No.Intermediate
DEFE-0011441-87-82-hydroxybenzoyl chloride
DEFE-00265-45-22-hydroxybenzamide
DEFE-0031218-69-52-(2-hydroxyphenyl)-4H-benzo[e][1,3]oxazin-4-one
DEFE-004619-67-04-hydrazinylbenzoic acid
OptimisedRoute 2Steps 4 · Total yield 22.8 g
Synthetic routes & intermediates Route 2
CodeCAS No.Intermediate
DEFE-00574511-44-72-(benzyloxy)benzonitrile
DEFE-0061492958-95-8methyl 2-(benzyloxy)benzimidate hydrochloride
DEFE-0071492958-41-4methyl 2-(benzyloxy)benzimidate
DEFE-0081441-87-82-hydroxybenzoyl chloride
DEFE-0091492957-96-62-(2-(benzyloxy)phenyl)-4H-benzo[e][1,3]oxazin-4-one
DEFE-010619-67-04-hydrazinylbenzoic acid

Frequently asked questions

What are the approved indications of Deferasirox?

Approved indications include: 地中海贫血, 铁超负荷, β-地中海贫血.

When does the Deferasirox patent expire?

No public expiry year is available for Deferasirox yet; this page updates once verified.

How many synthesis routes are recorded for Deferasirox?

2 synthesis routes are recorded; the shortest is 2 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Deferasirox intermediates?

All intermediates in Deferasirox routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Deferasirox intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-24