甲磺酸沙非胺
Tier C — Watch / tradeSafinamide Mesylate
Targets：MAOB
Brand：Equfina、Xadago
Indications (approved)：帕金森病
Regional status
Synthetic routes & intermediates3 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| SAFI-001 | 456-42-8 | 1-(chloromethyl)-3-fluorobenzene |
| SAFI-002 | 123-08-0Available | 4-hydroxybenzaldehyde |
| SAFI-003 | 66742-57-2 | 4-((3-fluorobenzyl)oxy)benzaldehyde |
| SAFI-004 | 33208-99-0 | (S)-2-aminopropanamide hydrochloride |
| Code | CAS No. | Intermediate |
|---|---|---|
| SAFI-005 | 35661-39-3 | (((9H-fluoren-9-yl)methoxy)carbonyl)-L-alanine |
| SAFI-006 | - | (S)-(9H-fluoren-9-yl)methyl (1-(methylamino)-1-oxopropan-2-yl)carbamate |
| SAFI-007 | - | (S)-2-amino-N-methylpropanamide |
| SAFI-008 | 211617-68-4 | 4-((triisopropylsilyl)oxy)benzaldehyde |
| SAFI-009 | - | (S,E)-N-methyl-2-((4-((triisopropylsilyl)oxy)benzylidene)amino)propanamide |
| SAFI-010 | - | (S)-N-methyl-2-((4-((triisopropylsilyl)oxy)benzyl)amino)propanamide |
| SAFI-011 | - | (S)-2-((4-hydroxybenzyl)amino)-N-methylpropanamide |
| SAFI-012 | 456-47-3 | (3-fluorophenyl)methanol |
| SAFI-013 | - | (S)-2-((4-((3-fluorobenzyl)oxy)benzyl)amino)-N-methylpropanamide |
| Code | CAS No. | Intermediate |
|---|---|---|
| SAFI-014 | 28490-56-4 | 1-fluoro-3-(iodomethyl)benzene |
| SAFI-015 | 623-05-2 | 4-(hydroxymethyl)phenol |
| SAFI-016 | 690969-16-5 | (4-((3-fluorobenzyl)oxy)phenyl)methanol |
| SAFI-017 | 1621168-04-4 | 1-fluoro-3-((4-(iodomethyl)phenoxy)methyl)benzene |
| SAFI-018 | 1351395-66-8 | - |
| SAFI-019 | 1621168-05-5 | - |
| SAFI-020 | - | - |
| SAFI-021 | - | - |
| SAFI-022 | 376325 | 2-((benzyloxy)methyl)oxirane |
| SAFI-023 | 14618-80-5 | (R)-2-((benzyloxy)methyl)oxirane |
| SAFI-024 | 89401-28-5 | (R)-1-(benzyloxy)propan-2-ol |
| SAFI-025 | - | (S)-((2-azidopropoxy)methyl)benzene |
| SAFI-026 | 35320-23-1 | (S)-2-aminopropan-1-ol |
Frequently asked questions
What are the approved indications of Safinamide Mesylate?
Approved indications include: 帕金森病.
When does the Safinamide Mesylate patent expire?
No public expiry year is available for Safinamide Mesylate yet; this page updates once verified.
How many synthesis routes are recorded for Safinamide Mesylate?
3 synthesis routes are recorded; the shortest is 3 steps with 61 kg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Safinamide Mesylate intermediates?
1 intermediate CAS of Safinamide Mesylate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Safinamide Mesylate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24