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Sotagliflozin · all drugs expiring in 2032 →

赛诺菲
Originator
2019
First approval
2032
Expiry (public)
$0.3B *
Peak sales
化学药
Type

Targets:SGLT2、SGLT1

Brand:INPEFA、Zynquista

Indications (approved):二型糖尿病、慢性肾功能不全、心脏衰竭

Regional status

US
批准上市
2023-05-26
EU
临床三期
2015-05-01
China
终止
2017-12-19
Japan
-

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 11 · Total yield 67.00 g (Sotagliflozin)
Synthetic routes & intermediates Route 1
CodeCAS No.Intermediate
SOTA-0017296-58-4Available(3S,4R,5S)-tetrahydro-2H-pyran-2,3,4,5-tetraol
SOTA-002114861-22-2Available(3aS,5S,6R,6aS)-5-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol
SOTA-0031103738-17-5Available(3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole-5-carboxylic acid
SOTA-004110-91-8Availablemorpholine
SOTA-0051103738-19-7Available((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone
SOTA-0061103738-29-9Available1-chloro-2-(4-ethoxybenzyl)-4-iodobenzene
SOTA-0071103738-30-2Available(4-chloro-3-(4-ethoxybenzyl)phenyl)((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanone
SOTA-0081384242-55-0Available(2S,3S,4R,5R,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-2,3,4,5-tetraol
SOTA-0091384242-56-1Available(2R,3S,4R,5S,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate
SOTA-0101018899-03-0Available(2S,3S,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triyl triacetate
SOTA-01119094-56-5Available2-chloro-5-iodobenzoic acid
SOTA-012281652-58-2Available2-chloro-5-iodobenzoyl chloride
SOTA-013103-73-1Availableethoxybenzene
SOTA-0141103738-26-6Available(2-chloro-5-iodophenyl)(4-ethoxyphenyl)methanone

Frequently asked questions

What are the approved indications of Sotagliflozin?

Approved indications include: 二型糖尿病, 慢性肾功能不全, 心脏衰竭.

When does the Sotagliflozin patent expire?

Based on public sources, the Sotagliflozin patent expires in 2032.

How many synthesis routes are recorded for Sotagliflozin?

1 synthesis routes are recorded; the shortest is 11 steps with 67.00 g (Sotagliflozin) total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Sotagliflozin intermediates?

14 intermediate CAS of Sotagliflozin are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Sotagliflozin intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-24