盐酸替立定

Tier C — Watch / trade

Tilidine Hydrochloride

Originator

2013

First approval

Expiry (public)

No sales data

Peak sales

化学药

Type

Targets：Opioid receptors

Brand：Valoron

Indications (approved)：疼痛

Regional status

China

批准上市

2013-06-03

Japan

Synthetic routes & intermediates2 routes

Originator routes × 0Optimised (non-patent) × 2Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OptimisedRoute 1Steps 5 · Total yield /

Synthetic routes & intermediates Route 1

Code	CAS No.	Intermediate
Tilidine Hydrochloride-001	100-39-0	1-(Bromomethyl)benzene
Tilidine Hydrochloride-002	105-53-3 Available	1,3-Diethyl propanedioate
Tilidine Hydrochloride-003	101-97-3	Ethyl 2-phenylacetate
Tilidine Hydrochloride-004	22286-82-4	Ethyl 2-phenylprop-2-enoate
Tilidine Hydrochloride-005	77627-82-8	2,2,2-Trichloroethyl (1E)-buta-1,3-dien-1-ylcarbamate
Tilidine Hydrochloride-006	-	2,2,2-Trichloroethyl trans-6-(ethoxycarbonyl)-6-phenyl-2-cyclohexen-1-carbamate
Tilidine Hydrochloride-007	-	(1R,6S)-6-Amino-1-phenyl-3-cyclohexene-1-carboxylic acid ethyl ester
Tilidine Hydrochloride-008	32447-90-8	Ethyl trans-2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate

OptimisedRoute 2Steps 1 · Total yield /

Synthetic routes & intermediates Route 2

Code	CAS No.	Intermediate
Tilidine Hydrochloride-009	139943-10-5	(1E)-N,N-Dimethylbuta-1,3-dien-1-amine
Tilidine Hydrochloride-004	22286-82-4	Ethyl 2-phenylprop-2-enoate

Frequently asked questions

What are the approved indications of Tilidine Hydrochloride?

Approved indications include: 疼痛.

When does the Tilidine Hydrochloride patent expire?

No public expiry year is available for Tilidine Hydrochloride yet; this page updates once verified.

How many synthesis routes are recorded for Tilidine Hydrochloride?

2 synthesis routes are recorded; the shortest is 1 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Tilidine Hydrochloride intermediates?

1 intermediate CAS of Tilidine Hydrochloride are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Tilidine Hydrochloride intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-24