Elobixibat Hydrate
Tier C — Watch / tradeElobixibat Hydrate
Targets：IBAT
Brand：Goofice
Indications (approved)：便秘
Regional status
Synthetic routes & intermediates2 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| ELOB-001 | - | 7-bromo-3,3-dibutyl-8-methoxy-5-phenyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepine 1,1-dioxide |
| ELOB-002 | - | 3,3-dibutyl-8-hydroxy-7-(methylthio)-5-phenyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepine 1,1-dioxide |
| ELOB-003 | 105-36-2Available | ethyl 2-bromoacetate |
| ELOB-004 | - | ethyl 2-((3,3-dibutyl-7-(methylthio)-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-8-yl)oxy)acetate |
| ELOB-005 | 439088-13-8 | 2-((3,3-dibutyl-7-(methylthio)-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-8-yl)oxy)acetic acid |
| ELOB-006 | 19883-41-1 | methyl (R)-2-amino-2-phenylacetate hydrochloride |
| ELOB-007 | - | (R)-tert-butyl 2-(2-(2-((3,3-dibutyl-7-(methylthio)-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-8-yl)oxy)acetamido)-2-phenylacetamido)acetate |
| ELOB-008 | - | 7-bromo-3,3-dibutyl-8-hydroxy-5-phenyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepine 1,1-dioxide |
| ELOB-009 | 6456-74-2 | ethyl 2-((7-bromo-3,3-dibutyl-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-8-yl)oxy)acetate |
| ELOB-010 | - | 2-((7-bromo-3,3-dibutyl-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-8-yl)oxy)acetic acid |
| Code | CAS No. | Intermediate |
|---|---|---|
| ELOB-011 | 358376-04-2 | (R)-methyl 2-(2-((3,3-dibutyl-7-(methylthio)-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-8-yl)oxy)acetamido)-2-phenylacetate |
| ELOB-003 | 105-36-2Available | ethyl 2-bromoacetate |
| ELOB-012 | - | (R)-2-(2-((3,3-dibutyl-7-(methylthio)-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-8-yl)oxy)acetamido)-2-phenylacetic acid |
| ELOB-013 | 358375-95-8 | 2-((7-bromo-3,3-dibutyl-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-8-yl)oxy)acetic acid |
| ELOB-005 | 439088-13-8 | 2-((3,3-dibutyl-7-(methylthio)-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-8-yl)oxy)acetic acid |
| ELOB-006 | 19883-41-1 | methyl (R)-2-amino-2-phenylacetate hydrochloride |
| ELOB-007 | - | (R)-tert-butyl 2-(2-(2-((3,3-dibutyl-7-(methylthio)-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-8-yl)oxy)acetamido)-2-phenylacetamido)acetate |
| ELOB-008 | - | 7-bromo-3,3-dibutyl-8-hydroxy-5-phenyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepine 1,1-dioxide |
| ELOB-009 | 6456-74-2 | ethyl 2-((7-bromo-3,3-dibutyl-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-8-yl)oxy)acetate |
| ELOB-010 | - | 2-((7-bromo-3,3-dibutyl-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-8-yl)oxy)acetic acid |
Frequently asked questions
What are the approved indications of Elobixibat Hydrate?
Approved indications include: 便秘.
When does the Elobixibat Hydrate patent expire?
No public expiry year is available for Elobixibat Hydrate yet; this page updates once verified.
How many synthesis routes are recorded for Elobixibat Hydrate?
2 synthesis routes are recorded; the shortest is 7 steps with 95.00 mg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Elobixibat Hydrate intermediates?
1 intermediate CAS of Elobixibat Hydrate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Elobixibat Hydrate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24