Betamethasone Dipropionate

Tier C — Watch / trade

Shionogi & Co., Ltd.

Originator

1975

First approval

Expiry (public)

No sales data

Peak sales

Small molecule

Type

Targets：GR

Brand：Alphatrex, Diprosone, Rinderon-DP, Diprolene AF, Sernivo

Indications (approved)：Psoriasis, Dermatitis, Pruritus, Eczema, 皮肤性疾病

Regional status

Approved

1975-01-29

Approved

1997-06-30

China

Approved

2006-05-17

Japan

Approved

1979-08-27

Synthetic routes & intermediates1 routes

Originator routes × 0Optimised (non-patent) × 1Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OptimisedRoute 1Steps 3 · Total yield 10.95 g

BETA-001—BETA-002—Betamethasone—API · Betamethasone Dipropionate

Code	CAS No.	Intermediate
BETA-001	-	(8S,9R,10S,13S,14S,16S,17R)-2'-ethoxy-2'-ethyl-9-fluoro-11-hydroxy-10,13,16-trimethyl-7,8,9,10,11,12,13,14,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,4'-[1,3]dioxane]-3,5'(6H)-dione
BETA-002	-	(8S,9R,10S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate
Betamethasone	-	(8S,9R,10S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

Frequently asked questions

What are the approved indications of Betamethasone Dipropionate?

Approved indications include: Psoriasis, Dermatitis, Pruritus, Eczema, 皮肤性疾病.

When does the Betamethasone Dipropionate patent expire?

No public expiry year is available for Betamethasone Dipropionate yet; this page updates once verified.

How many synthesis routes are recorded for Betamethasone Dipropionate?

1 synthesis routes are recorded; the shortest is 3 steps with 10.95 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Betamethasone Dipropionate intermediates?

All intermediates in Betamethasone Dipropionate routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Betamethasone Dipropionate intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-27