德拉沙星
Tier C — Watch / tradeDelafloxacin · all drugs expiring in 2029 →
Targets：Topoisomerase IV、Bacterial DNA gyrase
Brand：Baxdela、Quofenix
Indications (approved)：社区获得性细菌肺炎、社区获得性肺炎、细菌性皮肤疾病、皮肤和皮肤结构感染
Regional status
Synthetic routes & intermediates2 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| DELAF-001 | 446-17-3 | 2,4,5-trifluorobenzoic acid |
| DELAF-002 | 98349-24-7 | ethyl 3-oxo-3-(2,4,5-trifluorophenyl)propanoate |
| DELAF-003 | 247069-27-8Available | 3,5-difluoropyridine-2,6-diamine |
| DELAF-004 | 875712-88-2 | (Z)-ethyl 3-((6-amino-3,5-difluoropyridin-2-yl)amino)-2-(2,4,5-trifluorobenzoyl)acrylate |
| DELAF-005 | 18621-18-6 | azetidin-3-ol hydrochloride |
| DELAF-006 | - | ethyl 1-(6-amino-3,5-difluoropyridin-2-yl)-6-fluoro-7-(3-(isobutyryloxy)azetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate |
| Code | CAS No. | Intermediate |
|---|---|---|
| DELAF-003 | 247069-27-8Available | 3,5-difluoropyridine-2,6-diamine |
| DELAF-005 | 18621-18-6 | azetidin-3-ol hydrochloride |
| DELAF-007 | 101987-86-4Available | ethyl 3-(3-chloro-2,4,5-trifluorophenyl)-3-oxopropanoate |
| DELAF-008 | 101987-87-5Available | (Z)-ethyl 2-(3-chloro-2,4,5-trifluorobenzoyl)-3-ethoxyacrylate |
| DELAF-009 | 339591-73-0 | (Z)-ethyl 3-((6-amino-3,5-difluoropyridin-2-yl)amino)-2-(3-chloro-2,4,5-trifluorobenzoyl)acrylate |
| DELAF-010 | - | ethyl 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate |
| DELAF-011 | - | ethyl 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate |
| DELAF-012 | - | sodium 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate |
Frequently asked questions
What are the approved indications of Delafloxacin?
Approved indications include: 社区获得性细菌肺炎, 社区获得性肺炎, 细菌性皮肤疾病, 皮肤和皮肤结构感染.
When does the Delafloxacin patent expire?
Based on public sources, the Delafloxacin patent expires in 2029.
How many synthesis routes are recorded for Delafloxacin?
2 synthesis routes are recorded; the shortest is 4 steps with 73 kg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Delafloxacin intermediates?
3 intermediate CAS of Delafloxacin are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Delafloxacin intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24