Diroximel fumarate
Tier C — Watch / tradeDiroximel fumarate
Targets:Nrf2
Brand:Vumerity
Indications (approved):多发性硬化、复发-缓解型多发性硬化
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

| Code | CAS No. | Intermediate |
|---|---|---|
| MONO-001 | 2759-87-8 | (E)-4-methoxy-4-oxobut-2-enoic acid |
| MONO-002 | 18190-44-8 | 1-(2-hydroxyethyl)pyrrolidine-2,5-dione |
Frequently asked questions
What are the approved indications of Diroximel fumarate?
Approved indications include: 多发性硬化, 复发-缓解型多发性硬化.
When does the Diroximel fumarate patent expire?
No public expiry year is available for Diroximel fumarate yet; this page updates once verified.
How many synthesis routes are recorded for Diroximel fumarate?
1 synthesis routes are recorded; the shortest is 1 steps with 1.03 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Diroximel fumarate intermediates?
All intermediates in Diroximel fumarate routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Diroximel fumarate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24