艾尔巴韦
Tier C — Watch / tradeElbasvir
Targets：NS5A
Brand：Erelsa
Indications (approved)：丙型肝炎
Regional status
Synthetic routes & intermediates3 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| ELBA-001 | 591-20-8 | 3-bromophenol |
| ELBA-002 | 35065-86-2 | 3-bromophenyl acetate |
| ELBA-003 | 30186-18-6 | 1-(4-bromo-2-hydroxyphenyl)ethan-1-one |
| ELBA-004 | 622-88-8 | (4-bromophenyl)hydrazine |
| ELBA-005 | 1369594-43-3 | (E)-5-bromo-2-(1-(2-(4-bromophenyl)hydrazineylidene)ethyl)phenol |
| ELBA-006 | 1246471-94-2 | 5-bromo-2-(5-bromo-1H-indol-2-yl)phenol |
| ELBA-007 | 618-31-5 | (dibromomethyl)benzene |
| ELBA-008 | 1369594-56-8 | 3,10-dibromo-6-phenyl-6H-benzo[5,6][1,3]oxazino[3,4-a]indole |
| ELBA-009 | 73183-34-3Available | 4,4,4',4',5,5,5',5'-octamethyl-2,2'-bi(1,3,2-dioxaborolane) |
| ELBA-010 | 1369594-57-9 | 6-phenyl-3,10-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6H-benzo[5,6][1,3]oxazino[3,4-a]indole |
| ELBA-011 | 1007882-59-8 | tert-butyl (S)-2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate |
| ELBA-012 | - | di-tert-butyl 2,2'-((6-phenyl-6H-benzo[5,6][1,3]oxazino[3,4-a]indole-3,10-diyl)bis(1H-imidazole-4,2-diyl))(2S,2'S)-bis(pyrrolidine-1-carboxylate) |
| ELBA-013 | 1369595-06-1 | (S)-6-phenyl-3,10-bis(2-((S)-pyrrolidin-2-yl)-1H-imidazol-4-yl)-6H-benzo[5,6][1,3]oxazino[3,4-a]indole |
| ELBA-014 | 74761-42-5 | (methoxycarbonyl)-D-valine |
| Code | CAS No. | Intermediate |
|---|---|---|
| ELBA-001 | 591-20-8 | 3-bromophenol |
| ELBA-011 | 1007882-59-8 | tert-butyl (S)-2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate |
| ELBA-013 | 1369595-06-1 | (S)-6-phenyl-3,10-bis(2-((S)-pyrrolidin-2-yl)-1H-imidazol-4-yl)-6H-benzo[5,6][1,3]oxazino[3,4-a]indole |
| ELBA-014 | 74761-42-5 | (methoxycarbonyl)-D-valine |
| ELBA-015 | 203314-28-7 | 2-(2,5-dibromophenyl)acetic acid |
| ELBA-016 | 1403991-82-1 | 3-bromophenyl 2-(2,5-dibromophenyl)acetate |
| ELBA-017 | 1403991-85-4 | 1-(4-bromo-2-hydroxyphenyl)-2-(2,5-dibromophenyl)ethan-1-one |
| ELBA-018 | 1585969-22-7 | 5-bromo-2-(2-(2,5-dibromophenyl)-1-iminoethyl)phenol |
| ELBA-019 | - | ((N-((1S,2S)-1,2-diphenyl-2-((3-phenylpropyl)amino)ethyl)-4-methylphenyl)sulfonamido)ruthenium(II) chloride |
| ELBA-020 | 1585969-24-9 | (R)-2-(1-amino-2-(2,5-dibromophenyl)ethyl)-5-bromophenol |
| ELBA-021 | 1585969-17-0 | (R)-5-bromo-2-(5-bromoindolin-2-yl)phenol |
| ELBA-022 | 1585969-16-9 | (6S,12aR)-3,10-dibromo-6-phenyl-12,12a-dihydro-6H-benzo[5,6][1,3]oxazino[3,4-a]indole |
| ELBA-023 | 1392102-38-3 | (S)-3,10-dibromo-6-phenyl-6H-benzo[5,6][1,3]oxazino[3,4-a]indole |
| ELBA-024 | - | di-tert-butyl 2,2'-(((S)-6-phenyl-6H-benzo[5,6][1,3]oxazino[3,4-a]indole-3,10-diyl)bis(1H-imidazole-4,2-diyl))(2S,2'S)-bis(pyrrolidine-1-carboxylate) |
| Code | CAS No. | Intermediate |
|---|---|---|
| ELBA-011 | 1007882-59-8 | tert-butyl (S)-2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate |
| ELBA-014 | 74761-42-5 | (methoxycarbonyl)-D-valine |
| ELBA-025 | - | tert-butyl (S)-2-(hydroxymethyl)pyrrolidine-1-carboxylate |
| ELBA-026 | 1007882-58-7 | tert-butyl (S)-2-(1H-imidazol-2-yl)pyrrolidine-1-carboxylate |
| ELBA-027 | 1713286-23-7 | tert-butyl (S)-2-(5-bromo-4-chloro-1H-imidazol-2-yl)pyrrolidine-1-carboxylate |
| ELBA-028 | 1713286-24-8 | tert-butyl (S)-2-(4-chloro-1H-imidazol-2-yl)pyrrolidine-1-carboxylate |
| ELBA-029 | 1713286-25-9 | (S)-4-chloro-2-(pyrrolidin-2-yl)-1H-imidazole |
| ELBA-030 | - | methyl ((R)-1-((S)-2-(4-chloro-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate |
| ELBA-031 | 1713286-22-6 | (S)-6-phenyl-3,10-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6H-benzo[5,6][1,3]oxazino[3,4-a]indole |
Frequently asked questions
What are the approved indications of Elbasvir?
Approved indications include: 丙型肝炎.
When does the Elbasvir patent expire?
No public expiry year is available for Elbasvir yet; this page updates once verified.
How many synthesis routes are recorded for Elbasvir?
3 synthesis routes are recorded; the shortest is 7 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Elbasvir intermediates?
1 intermediate CAS of Elbasvir are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Elbasvir intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24