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半琥珀酸拉米地坦

Tier C — Watch / trade

Lasmiditan hemisuccinate

礼来制药
Originator
2019
First approval
-
Expiry (public)
No sales data
Peak sales
化学药
Type

Targets5-HT1F

Brandレイボー、Reyvow、RAYVOW

Indications (approved)偏头痛

Regional status

US
撤市
EU
批准上市
2022-08-17
China
终止
2022-01-29
Japan
批准上市
2022-01-20

Synthetic routes & intermediates2 routes

Originator routes × 1Optimised (non-patent) × 1Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 7 · Total yield 5.12 g (Lasmiditan Hydrochloride)
Synthetic routes & intermediates Route 1
CodeCAS No.Intermediate
LASM-001498-94-2Availablepiperidine-4-carboxylic acid
LASM-00268947-43-31-methylpiperidine-4-carboxylic acid
LASM-0037462-84-21-methylpiperidine-4-carbonyl chloride hydrochloride
LASM-004613678-09-4N,N,1-trimethylpiperidine-4-carboxamide
LASM-005626-05-12,6-dibromopyridine
LASM-006613678-08-3(6-bromopyridin-2-yl)(1-methylpiperidin-4-yl)methanone
LASM-007613678-03-8(6-aminopyridin-2-yl)(1-methylpiperidin-4-yl)methanone
LASM-00879538-29-72,4,6-trifluorobenzoyl chloride
OptimisedRoute 2Steps 5 · Total yield /
Synthetic routes & intermediates Route 2
CodeCAS No.Intermediate
LASM-007613678-03-8(6-aminopyridin-2-yl)(1-methylpiperidin-4-yl)methanone
LASM-00879538-29-72,4,6-trifluorobenzoyl chloride
LASM-009109-09-12-chloropyridine
LASM-010215950-19-9N-methoxy-N,1-dimethylpiperidine-4-carboxamide
LASM-011225112-16-3(6-chloropyridin-2-yl)(1-methylpiperidin-4-yl)methanone
LASM-0121013-88-3diphenylmethanimine
LASM-013-(6-((diphenylmethylene)amino)pyridin-2-yl)(1-methylpiperidin-4-yl)methanone

Frequently asked questions

What are the approved indications of Lasmiditan hemisuccinate?

Approved indications include: 偏头痛.

When does the Lasmiditan hemisuccinate patent expire?

No public expiry year is available for Lasmiditan hemisuccinate yet; this page updates once verified.

How many synthesis routes are recorded for Lasmiditan hemisuccinate?

2 synthesis routes are recorded; the shortest is 5 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Lasmiditan hemisuccinate intermediates?

1 intermediate CAS of Lasmiditan hemisuccinate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Lasmiditan hemisuccinate intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-24