塞利尼索
Tier C — Watch / tradeSelinexor · all drugs expiring in 2030 →
Targets：XPO1
Brand：XPOVIO、Nexpovio、Xpovio、希维奥
Indications (approved)：弥漫性大B-细胞淋巴瘤、多发性骨髓瘤
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| SELI-001 | 27126-93-8 | 3,5-bis(trifluoromethyl)benzonitrile |
| SELI-002 | 317319-15-6 | 3,5-bis(trifluoromethyl)benzothioamide |
| SELI-003 | 1333154-10-1 | 3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazole |
| SELI-004 | 1388842-43-0 | isopropyl (Z)-3-iodoacrylate |
| SELI-005 | 1421923-95-6 | isopropyl (Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylate |
| SELI-006 | 1388842-44-1 | (Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylic acid |
| SELI-007 | 54608-52-5 | 2-hydrazinylpyrazine |
Frequently asked questions
What are the approved indications of Selinexor?
Approved indications include: 弥漫性大B-细胞淋巴瘤, 多发性骨髓瘤.
When does the Selinexor patent expire?
Based on public sources, the Selinexor patent expires in 2030.
How many synthesis routes are recorded for Selinexor?
1 synthesis routes are recorded; the shortest is 5 steps with 40 mg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Selinexor intermediates?
All intermediates in Selinexor routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Selinexor intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24