← Back to patent-cliff list
CAS 102096-25-3
2,2,2-Trifluoroethyl 2-methylpropanoate2,2,2-trifluoroethyl isobutyrate
Codes: Molnupiravir-042, LONA-022
Application context (from source-drug indications)
COVID-19Molnupiravir呼吸道合胞体病毒感染MolnupiravirInfluenza virus infectionMolnupiravirRenal impairmentMolnupiravirHepatic function declineMolnupiravir早衰综合征Lonafarnib丁型肝炎Lonafarnib幕上肿瘤Lonafarnib神经胶质肉瘤Lonafarnib慢性丁型肝炎LonafarnibNon-small cell lung cancerLonafarnib
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Molnupiravir | Tier B — Position early | - |
| Lonafarnib | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
N-Hydroxy-2',3'-O-(1-methylethylidene)cytidine→2,2,2-Trifluoroethyl 2-methylpropanoate→1-[(3aR,4R,6R,6aR)-6-(Hydroxymethyl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d][1,3]dioxol-4-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione<-fgf->2',3'-O-Isopropylideneuridine→Hydroxylammonium chloride→Acetone O-isobutyryloxime→Ethenyl 2-methylpropanoate→N-Hydroxy-2',3'-O-(1-methylethylidene)-5'-O-(2-methylpropanoyl)cytidine→2',3'-O-(1-Methylethylidene)-5'-O-(2-methylpropanoyl)uridine
3,10-dibromo-8-chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine→(R)-3,10-dibromo-8-chloro-11-(piperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine→2,2,2-trifluoroethyl isobutyrate→1-(4-(3,10-dibromo-8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidin-1-yl)-2-methylpropan-1-one→3,10-dibromo-8-chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Taizhou GMP-like Site | ((3aR,4R,6R,6aR)-6-(4-(hydroxyamino)-2-oxopyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl isobutyrate Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.