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CAS 102691-36-1
2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidoite
Codes: Miltefosine-018
Application context (from source-drug indications)
利什曼原虫感染Miltefosine皮肤利什曼病MiltefosineChronic urticariaMiltefosine内脏利什曼病Miltefosine粘膜皮肤利什曼病Miltefosine
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Miltefosine | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-Cyano-2-hydroxyethane→2-Cyanoethyl phosphorodichloridoite→Bis(isopropyl)amine→2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidoite→2-Hydroxy-N,N,N-trimethylethan-1-aminium tetraphenylborate(1-)→2-([(2-Cyanoethoxy)[di(propan-2-yl)amino]phosphanyl]oxy)-N,N,N-trimethylethan-1-aminium tetraphenylborate(1-)→1-Hexadecanol
Intermediates available on this site
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