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CAS 1028634-76-5
methyl ((S)-1-(((2S,3S)-4-(2-((S)-2-amino-3,3-dimethylbutanoyl)-1-(4-(pyridin-2-yl)benzyl)hydrazinyl)-3-hydroxy-1-phenylbutan-2-yl)amino)-3,3-dimethyl-1-oxobutan-2-yl)carbamate
Codes：ATAZ-036
Application context (from source-drug indications)
HIV感染硫酸阿扎那韦/考比司他
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 硫酸阿扎那韦/考比司他Atazanavir Sulfate/Cobicistat | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
tert-butyl ((S)-1-((R)-oxiran-2-yl)-2-phenylethyl)carbamate→(S)-2-((methoxycarbonyl)amino)-3,3-dimethylbutanoic acid→2-(4-(hydrazinylmethyl)phenyl)pyridine→(S)-2-(((benzyloxy)carbonyl)amino)-3,3-dimethylbutanoic acid→benzyl (S)-(3,3-dimethyl-1-oxo-1-(2-(4-(pyridin-2-yl)benzyl)hydrazinyl)butan-2-yl)carbamate→benzyl ((S)-1-(2-((2S,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutyl)-2-(4-(pyridin-2-yl)benzyl)hydrazinyl)-3,3-dimethyl-1-oxobutan-2-yl)carbamate→benzyl ((S)-1-(2-((2S,3S)-3-amino-2-hydroxy-4-phenylbutyl)-2-(4-(pyridin-2-yl)benzyl)hydrazinyl)-3,3-dimethyl-1-oxobutan-2-yl)carbamate hydrochloride→methyl ((5S,10S,11S,14S)-11-benzyl-5-(tert-butyl)-10-hydroxy-15,15-dimethyl-3,6,13-trioxo-1-phenyl-8-(4-(pyridin-2-yl)benzyl)-2-oxa-4,7,8,12-tetraazahexadecan-14-yl)carbamate→methyl ((S)-1-(((2S,3S)-4-(2-((S)-2-amino-3,3-dimethylbutanoyl)-1-(4-(pyridin-2-yl)benzyl)hydrazinyl)-3-hydroxy-1-phenylbutan-2-yl)amino)-3,3-dimethyl-1-oxobutan-2-yl)carbamate
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