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CAS 1088110-90-0
ethyl (2,3-dihydroxypropyl)(3-fluoro-4-morpholinophenyl)carbamate
Codes: LINE-014
Application context (from source-drug indications)
非复杂性皮肤和皮肤结构感染LinezolidPneumoniaLinezolidComplicated skin and skin structure infectionLinezolidBacteraemiaLinezolidBacterial infectionLinezolidHealthcare-associated pneumoniaLinezolid
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Linezolid | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
3-fluoro-4-morpholinoaniline→N-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-3-fluoro-4-morpholinoaniline→N-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-3-fluoro-4-morpholinoaniline→ethyl carbonochloridate→ethyl ((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)(3-fluoro-4-morpholinophenyl)carbamate→ethyl (2,3-dihydroxypropyl)(3-fluoro-4-morpholinophenyl)carbamate→ethyl (3-fluoro-4-morpholinophenyl)(2-oxoethyl)carbamate→(R)-N-((R)-1-hydroxy-4-methyl-1,1-diphenylpentan-2-yl)pyrrolidine-2-carboxamide→ethyl (S)-(3-fluoro-4-morpholinophenyl)(2-hydroxy-4-oxopentyl)carbamate→ethyl (S,E)-(3-fluoro-4-morpholinophenyl)(2-hydroxy-4-(hydroxyimino)pentyl)carbamate→(S,E)-3-(3-fluoro-4-morpholinophenyl)-5-(2-(hydroxyimino)propyl)oxazolidin-2-one
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