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CAS 109425-55-0
Fmoc-Orn(Boc)-OHN5-(tert-Butoxycarbonyl)-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine
Codes: Atosiban-004
Application context (from source-drug indications)
产科分娩（早产）Atosiban acetate早产（孕37周前）Atosiban acetateEndometriosisAtosiban acetate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Atosiban acetate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
N-(9H-Fluoren-9-ylmethoxycarbonyl)glycine→Resin bound 9H-fluoren-9-ylmethyl (2-amino-2-oxoethyl)carbamate→Resin bound glycinamide→Fmoc-Orn(Boc)-OH→Resin bound S-trityl-L-cysteinyl-L-prolyl-N5-(tert-butoxycarbonyl)-L-ornithylglycinamide→Resin bound N5-(tert-butoxycarbonyl)-L-ornithylglycinamide→N-(9-Fluorenylmethoxycarbonyl)-L-proline→Resin bound L-prolyl-N5-(tert-butoxycarbonyl)-L-ornithylglycinamide→N-[[(9H-Fluoren-9-yl)methoxy]carbonyl]-S-(triphenylmethyl)-L-cysteine→N2-[[(9H-Fluoren-9-yl)methoxy]carbonyl]-N-(triphenylmethyl)-L-asparagine→Resin bound N-trityl-L-asparaginyl-S-trityl-L-cysteinyl-L-prolyl-N5-(tert-butoxycarbonyl)-L-ornithylglycinamide→O-tert-Butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-threonine→Resin bound O-tert-butyl-L-threonyl-N-trityl-L-asparaginyl-S-trityl-L-cysteinyl-L-prolyl-N5-(tert-butoxycarbonyl)-L-ornithylglycinamide
Resin bound glycine→CTC resin bound N5-(tert-butoxycarbonyl)-L-ornithylglycine→CTC resin bound L-prolyl-N5-(tert-butoxycarbonyl)-L-ornithylglycine→S-(Acetamidomethyl)-N-[[(9H-fluoren-9-yl)methoxy]carbonyl]-L-cysteine→CTC resin bouond S-(triphenylmethyl)-L-cysteinyl-L-prolyl-N5-(tert-butoxycarbonyl)-L-ornithylglycine→CTC resin bound N-(triphenylmethyl)-L-asparaginyl-S-(acetamidomethyl)-L-cysteinyl-L-prolyl-N5-(tert-butoxycarbonyl)-L-ornithylglycine→N-(9H-Fluoren-9-ylmethoxycarbonyl)glycine→N5-(tert-Butoxycarbonyl)-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine→N-(9-Fluorenylmethoxycarbonyl)-L-proline→Nalpha-(9-Fluorenylmethoxycarbonyl)-Ngamma-trityl-L-asparagine
N5-(tert-Butoxycarbonyl)-N2-[[(9H-fluoren-9-yl)methoxy]carbonyl]-L-ornithylglycinamide→N5-(tert-Butoxycarbonyl)-L-ornithylglycinamide→O-Ethyl-N-[3-[(triphenylmethyl)sulfanyl]propanoyl]-D-tyrosyl-L-isoleucyl-L-threonyl-N-(triphenylmethyl)-L-asparaginyl-S-(acetamidomethyl)-L-cysteinyl-L-proline→O-Ethyl-N-[3-[(triphenylmethyl)sulfanyl]propanoyl]-D-tyrosyl-L-isoleucyl-L-threonyl-N-(triphenylmethyl)-L-asparaginyl-S-(acetamidomethyl)-L-cysteinyl-L-prolyl-N5-(tert-butoxycarbonyl)-L-ornithylglycinamide→O-Ethyl-N-(3-sulfanylpropanoyl)-yITNS-(acetamidomethyl)-CPL-ornithylG-NH2 trifluoroacetic acid→N5-(tert-Butoxycarbonyl)-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine→2-Aminoacetamide hydrochloride
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