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CAS 115424-07-2
Benzyl [(2S)-1-iodo-3-(4-methoxyphenyl)propan-2-yl]carbamate
Codes：Tamsulosin Hydrochloride-075
Application context (from source-drug indications)
勃起功能障碍他达拉非/坦洛新前列腺增生他达拉非/坦洛新下尿路症状琥珀酸索利那新/盐酸坦洛新前列腺增生琥珀酸索利那新/盐酸坦洛新膀胱过度活动症琥珀酸索利那新/盐酸坦洛新药物相关的副作用和不良反应琥珀酸索利那新/盐酸坦洛新膀胱颈梗阻琥珀酸索利那新/盐酸坦洛新前列腺增生度他雄胺/盐酸坦洛新
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 他达拉非/坦洛新Tadalafil/Tamsulosin | Tier C — Watch / trade | - |
| 琥珀酸索利那新/盐酸坦洛新Solifenacin Succinate/Tamsulosin Hydrochloride | Tier C — Watch / trade | - |
| 度他雄胺/盐酸坦洛新Dutasteride/Tamsulosin Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-Methoxybenzaldehyde→2-Acetamidoacetic acid→(4E)-4-(4-Methoxybenzylidene)-2-methyl-1,3-oxazol-5(4H)-one→(2E)-2-(Acetylamino)-3-(4-methoxyphenyl)prop-2-enoic acid→N-Acetyl-O-methyl-L-tyrosine→O-Methyl-L-tyrosine→Ethyl O-methyl-L-tyrosinate→Ethyl N-[(benzyloxy)carbonyl]-O-methyl-L-tyrosinate→Benzyl [(2S)-1-hydroxy-3-(4-methoxyphenyl)propan-2-yl]carbamate→(2S)-2-[[(Benzyloxy)carbonyl]amino]-3-(4-methoxyphenyl)propyl 4-methylbenzenesulfonate→Benzyl [(2S)-1-iodo-3-(4-methoxyphenyl)propan-2-yl]carbamate→Benzyl [(2R)-1-(4-methoxyphenyl)propan-2-yl]carbamate
4-Methoxybenzaldehyde→2-Acetamidoacetic acid→(4E)-4-(4-Methoxybenzylidene)-2-methyl-1,3-oxazol-5(4H)-one→(2E)-2-(Acetylamino)-3-(4-methoxyphenyl)prop-2-enoic acid→N-Acetyl-O-methyl-L-tyrosine→O-Methyl-L-tyrosine→Ethyl O-methyl-L-tyrosinate→Ethyl N-[(benzyloxy)carbonyl]-O-methyl-L-tyrosinate→Benzyl [(2S)-1-hydroxy-3-(4-methoxyphenyl)propan-2-yl]carbamate→(2S)-2-[[(Benzyloxy)carbonyl]amino]-3-(4-methoxyphenyl)propyl 4-methylbenzenesulfonate→Benzyl [(2S)-1-iodo-3-(4-methoxyphenyl)propan-2-yl]carbamate→Benzyl [(2R)-1-(4-methoxyphenyl)propan-2-yl]carbamate
4-Methoxybenzaldehyde→2-Acetamidoacetic acid→(4E)-4-(4-Methoxybenzylidene)-2-methyl-1,3-oxazol-5(4H)-one→(2E)-2-(Acetylamino)-3-(4-methoxyphenyl)prop-2-enoic acid→N-Acetyl-O-methyl-L-tyrosine→O-Methyl-L-tyrosine→Ethyl O-methyl-L-tyrosinate→Ethyl N-[(benzyloxy)carbonyl]-O-methyl-L-tyrosinate→Benzyl [(2S)-1-hydroxy-3-(4-methoxyphenyl)propan-2-yl]carbamate→(2S)-2-[[(Benzyloxy)carbonyl]amino]-3-(4-methoxyphenyl)propyl 4-methylbenzenesulfonate→Benzyl [(2S)-1-iodo-3-(4-methoxyphenyl)propan-2-yl]carbamate→Benzyl [(2R)-1-(4-methoxyphenyl)propan-2-yl]carbamate
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