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CAS 116298-21-6

(1R,2R,4R,10R,11S,14S,16S,18S,19S)-10,14-dimethylhexacyclo[9.8.0.0(2,4).0(5,10).0(14,19).0(16,18)]nonadec-5-ene-7,15-dione

Codes:(I)169995-3-a

Application context (from source-drug indications)

避孕屈螺酮口腔炎,口疮屈螺酮经前焦虑性障碍屈螺酮经前期综合征屈螺酮痛经屈螺酮抑郁屈螺酮

Source drugs (routes using this intermediate)

DrugTierExpiry
屈螺酮DrospirenoneTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

屈螺酮优化路线steps: 2total yield: /
(1R,2R,4R,10R,11S,14S,16S,18S,19S)-10,14-dimethylhexacyclo[9.8.0.0(2,4).0(5,10).0(14,19).0(16,18)]nonadec-5-ene-7,15-dione→2-(1-ethoxyethoxy)but-3-enenitrile→(2E)-2-(1-ethoxyethoxy)-4-[(1R,2R,4R,10R,11S,14S,15S,16S,18S,19S)-15-hydroxy-10,14-dimethyl-7-oxohexacyclo[9.8.0.0(2,4).0(5,10).0(14,19).0(16,18)]nonadec-5-en-15-yl]but-2-enenitrile

Intermediates available on this site

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