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CAS 1199228-78-8
(2R)-N-Benzyl-1-(4-methoxyphenyl)propan-2-amine hydrogen chloride
Codes：Formoterol Fumarate-005
Application context (from source-drug indications)
哮喘布地奈德/富马酸福莫特/格隆溴铵慢性阻塞性肺疾病布地奈德/富马酸福莫特/格隆溴铵慢性阻塞性肺疾病富马酸福莫特罗/格隆溴铵
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 布地奈德/富马酸福莫特/格隆溴铵Budesonide/Formoterol fumarate/Glycopyrronium Bromide | Tier B — Position early | - |
| 富马酸福莫特罗/格隆溴铵Formoterol Fumarate/Glycopyrrolate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-(4-Hydroxy-3-nitrophenyl)ethan-1-one→1-(4-(Benzyloxy)-3-nitrophenyl)ethanone→1-(4-(Benzyloxy)-3-nitrophenyl)-2-bromoethanone→(2R*)-N-Benzyl-1-(4-methoxyphenyl)propan-2-amine→(2R)-N-Benzyl-1-(4-methoxyphenyl)propan-2-amine hydrogen chloride→2-[Benzyl[(2R*)-1-(4-methoxyphenyl)propan-2-yl]amino]-1-[4-(benzyloxy)-3-nitrophenyl]ethanone→(1R*)-2-[Benzyl[(2R*)-1-(4-methoxyphenyl)propan-2-yl]amino]-1-[4-(benzyloxy)-3-nitrophenyl]ethanol→(1R*)-1-[3-Amino-4-(benzyloxy)phenyl]-2-[benzyl[(2R*)-1-(4-methoxyphenyl)propan-2-yl]amino]ethanol→Acido formico→Amide c1→N-[5-[(1R*)-2-[Benzyl[(2R*)-1-(4-methoxyphenyl)propan-2-yl]amino]-1-hydroxyethyl]-2-(benzyloxy)phenyl]formamide→N-[2-Hydroxy-5-[1(R*)-hydroxy-2-[1(R*)-methyl-2-(4-methoxyphenyl)ethylamino]ethyl]phenyl]formamide
1-(4-Hydroxy-3-nitrophenyl)ethan-1-one→1-(4-(Benzyloxy)-3-nitrophenyl)ethanone→1-(4-(Benzyloxy)-3-nitrophenyl)-2-bromoethanone→(2R*)-N-Benzyl-1-(4-methoxyphenyl)propan-2-amine→(2R)-N-Benzyl-1-(4-methoxyphenyl)propan-2-amine hydrogen chloride→2-[Benzyl[(2R*)-1-(4-methoxyphenyl)propan-2-yl]amino]-1-[4-(benzyloxy)-3-nitrophenyl]ethanone→(1R*)-2-[Benzyl[(2R*)-1-(4-methoxyphenyl)propan-2-yl]amino]-1-[4-(benzyloxy)-3-nitrophenyl]ethanol→(1R*)-1-[3-Amino-4-(benzyloxy)phenyl]-2-[benzyl[(2R*)-1-(4-methoxyphenyl)propan-2-yl]amino]ethanol→Acido formico→Amide c1→N-[5-[(1R*)-2-[Benzyl[(2R*)-1-(4-methoxyphenyl)propan-2-yl]amino]-1-hydroxyethyl]-2-(benzyloxy)phenyl]formamide→N-[2-Hydroxy-5-[1(R*)-hydroxy-2-[1(R*)-methyl-2-(4-methoxyphenyl)ethylamino]ethyl]phenyl]formamide
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