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CAS 122853-01-4

2,2,2-trifluoro-N-(2-(1-methyl-1H-indol-2-yl)ethyl)acetamide

Codes: ALOS-008

Application context (from source-drug indications)

Irritable bowel syndromeAlosetron Hydrochloride

Source drugs (routes using this intermediate)

DrugTierExpiry
Alosetron HydrochlorideTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Alosetron HydrochlorideOptimised routesteps: 3total yield: /
2-(1-methyl-1H-indol-2-yl)ethan-1-amine→2,2,2-trifluoro-N-(2-(1-methyl-1H-indol-2-yl)ethyl)acetamide→5-(chloromethyl)-N,N,4-trimethyl-1H-imidazole-1-sulfonamide→N-((1-(N,N-dimethylsulfamoyl)-5-methyl-1H-imidazol-4-yl)methyl)-2,2,2-trifluoro-N-(2-(1-methyl-1H-indol-2-yl)ethyl)acetamide

Intermediates available on this site

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