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CAS 1233378-72-7
(R)-3-(1-((methylsulfonyl)oxy)ethyl)phenyl methanesulfonate3-[(1R)-1-[(Methanesulfonyl)oxy]ethyl]phenyl methanesulfonate
Codes: RIVAT-011, (III)145089-11-a
Application context (from source-drug indications)
Alzheimer's diseaseRivastigmine TartrateDementiaRivastigmine TartrateParkinson's diseaseRivastigmine Tartrate抗胆碱能综合征Rivastigmine Tartrate神经行为学表现Rivastigmine TartrateCognitive impairmentRivastigmine Tartrate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Rivastigmine Tartrate | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
ethyl(methyl)carbamic chloride→1-(3-hydroxyphenyl)ethan-1-one→(R)-3-(1-hydroxyethyl)phenol→(R)-3-(1-((methylsulfonyl)oxy)ethyl)phenyl methanesulfonate→(S)-3-(1-(dimethylamino)ethyl)phenyl methanesulfonate→(S)-3-(1-(dimethylamino)ethyl)phenol
1-(3-Hydroxyphenyl)ethanone→3-[1(R)-Hydroxyethyl]phenol→3-[(1R)-1-[(Methanesulfonyl)oxy]ethyl]phenyl methanesulfonate→Dimethylamine anhydrous→3-[(1S)-1-(Dimethylamino)ethyl]phenyl methanesulfonate→(-)-3-((1S)-1-(Dimethylamino)ethyl)phenol→N-Ethyl-N-methylcarbamic chloride→(S)-3-(1-(Dimethylamino)ethyl)phenyl ethyl(methyl)carbamate→3-Acetylphenyl ethyl(methyl)carbamate→3-[(1R)-1-Hydroxyethyl]phenyl ethyl(methyl)carbamate→(1R)-1-(3-[[Ethyl(methyl)carbamoyl]oxy]phenyl)ethyl methanesulfonate
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