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CAS 1240383-40-7
(8'S,9'S,10'R,13'S,14'S)-13'-ethyl-11'-methylene-1',6',7',8',9',10',11',12',13',14',15',16'-dodecahydro-2'H-dispiro[[1,3]dioxolane-2,3'-cyclopenta[a]phenanthrene-17',2''-[1,3]dioxolane]
Codes: ETON-004
Application context (from source-drug indications)
ContraceptionEtonogestrelAcquired immunodeficiency syndromeEtonogestrelDysmenorrhoeaEtonogestrel血崩EtonogestrelBenign prostatic hyperplasiaEtonogestrel月经失调Etonogestrel
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Etonogestrel | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(8S,9S,10R,11R,13S,14S)-13-ethyl-11-hydroxy-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione→(8'S,9'S,10'R,13'S,14'S)-13'-ethyl-1',2',6',7',8',9',10',12',13',14',15',16'-dodecahydro-11'H-dispiro[[1,3]dioxolane-2,3'-cyclopenta[a]phenanthrene-17',2''-[1,3]dioxolan]-11'-one→methyltriphenylphosphonium bromide→(8'S,9'S,10'R,13'S,14'S)-13'-ethyl-11'-methylene-1',6',7',8',9',10',11',12',13',14',15',16'-dodecahydro-2'H-dispiro[[1,3]dioxolane-2,3'-cyclopenta[a]phenanthrene-17',2''-[1,3]dioxolane]→(8S,9S,10R,13S,14S)-13-ethyl-11-methylene-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione→pyrrolidine→(8S,9S,10R,13S,14S)-13-ethyl-11-methylene-3-(pyrrolidin-1-yl)-1,2,7,8,9,10,11,12,13,14,15,16-dodecahydro-17H-cyclopenta[a]phenanthren-17-one→ethyne→(8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylene-3-(pyrrolidin-1-yl)-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol
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