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CAS 1241387-60-9
methyl (Z)-2-acetamido-3-(3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)acrylate
Codes: ZOLM-021
Application context (from source-drug indications)
MigraineZolmitriptan
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Zolmitriptan | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4,4-diethoxy-N,N-dimethylbutan-1-amine→4-bromoaniline→(4-bromophenyl)hydrazine→2-(5-bromo-1H-indol-3-yl)-N,N-dimethylethan-1-amine→methyl 2-acetamidoacrylate→methyl (Z)-2-acetamido-3-(3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)acrylate→methyl (S)-2-acetamido-3-(3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)propanoate→(S)-N-(1-(3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)-3-hydroxypropan-2-yl)acetamide→(S)-2-amino-3-(3-(2-aminoethyl)-1H-indol-5-yl)propan-1-ol hydrochloride
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