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CAS 1244971-54-7

(E)-2-((dimethylamino)methylene)-3-oxo-N-(4-(trifluoromethyl)phenyl)butanamide

Codes: LEFU-004

Application context (from source-drug indications)

Rheumatoid arthritisLeflunomide狼疮肾炎LeflunomidePsoriatic arthritisLeflunomideMyelodysplastic syndromeLeflunomideLymphomaLeflunomideSolid tumourLeflunomide

Source drugs (routes using this intermediate)

DrugTierExpiry
LeflunomideTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

LeflunomideOptimised routesteps: 2total yield: 14.8 g
3-oxo-N-(4-(trifluoromethyl)phenyl)butanamide→(E)-2-((dimethylamino)methylene)-3-oxo-N-(4-(trifluoromethyl)phenyl)butanamide

Intermediates available on this site

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