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CAS 1253391-55-7
(8'S,9'S,10'R,13'S,14'S)-13'-ethyl-1',2',6',7',8',9',10',12',13',14',15',16'-dodecahydro-11'H-dispiro[[1,3]dioxolane-2,17'-cyclopenta[a]phenanthrene-3',2''-[1,3]dithiolan]-11'-one
Codes: ETON-012
Application context (from source-drug indications)
ContraceptionEtonogestrelAcquired immunodeficiency syndromeEtonogestrelDysmenorrhoeaEtonogestrel血崩EtonogestrelBenign prostatic hyperplasiaEtonogestrel月经失调Etonogestrel
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Etonogestrel | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(8S,9S,10R,11R,13S,14S)-13-ethyl-11-hydroxy-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione→ethyne→(8S,9S,10R,11R,13S,14S)-13-ethyl-11-hydroxy-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dithiolan]-17(2H)-one→(8'S,9'S,10'R,11'R,13'S,14'S)-13'-ethyl-1',6',7',8',9',10',11',12',13',14',15',16'-dodecahydro-2'H-dispiro[[1,3]dioxolane-2,17'-cyclopenta[a]phenanthrene-3',2''-[1,3]dithiolan]-11'-ol→(8'S,9'S,10'R,13'S,14'S)-13'-ethyl-1',2',6',7',8',9',10',12',13',14',15',16'-dodecahydro-11'H-dispiro[[1,3]dioxolane-2,17'-cyclopenta[a]phenanthrene-3',2''-[1,3]dithiolan]-11'-one→(8S,9S,10R,13S,14S)-13-ethyl-11-methylene-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dithiolan]-17(2H)-one→(8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylene-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dithiolan]-17-ol
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