← Back to patent-cliff list
CAS 1275616-59-5
methyl 3-((3S)-7-bromo-2-((2-hydroxypropyl)amino)-5-(pyridin-2-yl)-3H-benzo[e][1,4]diazepin-3-yl)propanoate
Codes：REMIB-010
Application context (from source-drug indications)
镇静苯磺酸瑞马唑仑麻醉苯磺酸瑞马唑仑
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 苯磺酸瑞马唑仑Remimazolam Besilate | Tier C — Watch / trade | 2030 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-amino-5-bromobenzoic acid→2-bromopyridine→(2-amino-5-bromophenyl)(pyridin-2-yl)methanone→(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-methoxy-5-oxopentanoic acid→methyl (S)-4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-((4-bromo-2-picolinoylphenyl)amino)-5-oxopentanoate→methyl (S)-3-(7-bromo-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanoate→dimorpholinophosphinic chloride→methyl (S)-3-(7-bromo-2-((dimorpholinophosphoryl)oxy)-5-(pyridin-2-yl)-3H-benzo[e][1,4]diazepin-3-yl)propanoate→1-aminopropan-2-ol→methyl 3-((3S)-7-bromo-2-((2-hydroxypropyl)amino)-5-(pyridin-2-yl)-3H-benzo[e][1,4]diazepin-3-yl)propanoate
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.