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CAS 1304512-36-4
Methyl N-[(benzyloxy)carbonyl]-D-phenylalanyl-N5-[N-(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-sulfonyl)carbamimidoyl]-L-ornithinate
Codes: (XII)443746-2-c
Application context (from source-drug indications)
下丘脑肥胖Setmelanotide Acetate巴德特-别德尔综合征Setmelanotide AcetateObesitySetmelanotide AcetatePrader-Willi综合征Setmelanotide Acetate垂体疾病Setmelanotide Acetate联合性垂体激素缺乏症Setmelanotide Acetate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Setmelanotide Acetate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
Methyl D-alanyl-L-histidyl-D-phenylalanyl-N5-[N-(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-sulfonyl)carbamimidoyl]-L-ornithinate→N-[Benzyloxycarbonyl]-D-phenylalanine→Methyl N5-[N-(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-sulfonyl)carbamimidoyl]-L-ornithinate hydrogen chloride→Methyl N-[(benzyloxy)carbonyl]-D-phenylalanyl-N5-[N-(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-sulfonyl)carbamimidoyl]-L-ornithinate→N-[(Benzyloxy)carbonyl]-D-alanyl-L-histidine→N-(Benzyloxycarbonyl)-D-alanine→(S)-2-Amino-3-(4-imidazolyl)propionic acid→Methyl N-[(benzyloxy)carbonyl]-D-alanyl-L-histidyl-D-phenylalanyl-N5-[N-(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-sulfonyl)carbamimidoyl]-L-ornithinate
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