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CAS 134458-52-9
(4R,5S)-4-methyl-3-(4-methylpentanoyl)-5-phenyloxazolidin-2-one
Codes: PREG-004
Application context (from source-drug indications)
FibromyalgiaPregabalinSeizurePregabalinPostherpetic neuralgiaPregabalin神经痛PregabalinPartial-onset seizurePregabalinDiabetic neuropathyPregabalin
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Pregabalin | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-methylpentanoic acid→4-methylpentanoyl chloride→lithium (4R,5S)-4-methyl-2-oxo-5-phenyloxazolidin-3-ide→(4R,5S)-4-methyl-3-(4-methylpentanoyl)-5-phenyloxazolidin-2-one→benzyl 2-bromoacetate→benzyl (S)-5-methyl-3-((4R,5S)-4-methyl-2-oxo-5-phenyloxazolidine-3-carbonyl)hexanoate→(S)-2-(2-(benzyloxy)-2-oxoethyl)-4-methylpentanoic acid→benzyl (S)-3-(hydroxymethyl)-5-methylhexanoate→benzyl (S)-5-methyl-3-((tosyloxy)methyl)hexanoate→benzyl (S)-3-(azidomethyl)-5-methylhexanoate
Intermediates available on this site
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