← Back to patent-cliff list
CAS 134866-14-1
Diphenylmethyl (2S,5R,6R)-6-[(tert-butoxycarbonyl)amino]-3,3-dimethyl-4,7-dioxo-4lambda4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Codes：Tazobactam Sodium-053
Application context (from source-drug indications)
腹腔感染他唑巴坦钠/头孢洛生呼吸机相关性肺炎他唑巴坦钠/头孢洛生泌尿系统感染他唑巴坦钠/头孢洛生社区获得性细菌肺炎他唑巴坦钠/头孢洛生肾盂肾炎他唑巴坦钠/头孢洛生医院获得性肺炎他唑巴坦钠/头孢洛生细菌感染头孢他啶/他唑巴坦钠呼吸道感染头孢他啶/他唑巴坦钠泌尿系统感染头孢他啶/他唑巴坦钠
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 他唑巴坦钠/头孢洛生Tazobactam Sodium/Ceftolozane | Tier C — Watch / trade | - |
| 头孢他啶/他唑巴坦钠Ceftazidime/Tazobactam Sodium | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(+)-6-Aminopenicillanic acid→(Diphenylmethylidene)hydrazine→(2S,5R)-2beta-[(Benzhydryloxy)carbonyl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane4-oxide→Diphenylmethyl (2S,4R,5R,6R)-6-amino-3,3-dimethyl-4,7-dioxo-4lambda4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate→(2S,5R,6R)-6-[(tert-Butoxycarbonyl)amino]-3,3-dimethyl-4,7-dioxo-4lambda4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid→Diphenylmethyl (2S,5R,6R)-6-[(tert-butoxycarbonyl)amino]-3,3-dimethyl-4,7-dioxo-4lambda4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
(+)-6-Aminopenicillanic acid→(Diphenylmethylidene)hydrazine→(2S,5R)-2beta-[(Benzhydryloxy)carbonyl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane4-oxide→Diphenylmethyl (2S,4R,5R,6R)-6-amino-3,3-dimethyl-4,7-dioxo-4lambda4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate→(2S,5R,6R)-6-[(tert-Butoxycarbonyl)amino]-3,3-dimethyl-4,7-dioxo-4lambda4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid→Diphenylmethyl (2S,5R,6R)-6-[(tert-butoxycarbonyl)amino]-3,3-dimethyl-4,7-dioxo-4lambda4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.