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CAS 1350653-23-4
5-fluoro-3-iodo-1H-pyrazolo[3,4-b]pyridine
Codes: VERI-007
Application context (from source-drug indications)
Heart failureVericiguatLeft ventricular dysfunctionVericiguat主动脉瓣病变Vericiguat主动脉瓣狭窄VericiguatCognitive impairmentVericiguatVariant anginaVericiguat
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Vericiguat | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2,6-dichloro-5-fluoronicotinonitrile→2,6-dichloro-5-fluoronicotinamide→2-chloro-5-fluoronicotinamide→2-chloro-5-fluoronicotinonitrile→5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine→isopentyl nitrite→5-fluoro-3-iodo-1H-pyrazolo[3,4-b]pyridine→1-(bromomethyl)-2-fluorobenzene→5-fluoro-1-(2-fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-b]pyridine→2-chloro-5-nitropyrimidine-4,6-diamine→2-(5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-5-nitropyrimidine-4,6-diamine→2-(5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidine-4,5,6-triamine
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Qualified Partner — East China API Works | 5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Nantong cGMP Site | Phenylazomalononitrile Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.