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CAS 1354691-72-7
tert-butyl (S)-3-((5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)amino)pyrrolidine-1-carboxylate
Codes: LENI-004
Application context (from source-drug indications)
原发性免疫缺陷疾病Leniolisib phosphatePI3Kδ过度活化综合征Leniolisib phosphate盆腔炎性疾病Leniolisib phosphate普通可变性免疫缺陷Leniolisib phosphate免疫缺陷性疾病Leniolisib phosphateSjögren's syndromeLeniolisib phosphate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Leniolisib phosphate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(S)-tert-butyl 3-aminopyrrolidine-1-carboxylate→6-benzyl-4-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine→tert-butyl (S)-3-((6-benzyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)amino)pyrrolidine-1-carboxylate→tert-butyl (S)-3-((5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)amino)pyrrolidine-1-carboxylate→5-bromo-2-methoxy-3-(trifluoromethyl)pyridine→tert-butyl (S)-3-((6-(6-methoxy-5-(trifluoromethyl)pyridin-3-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)amino)pyrrolidine-1-carboxylate→2-methoxy-3-(trifluoromethyl)pyridine
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