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CAS 136522-33-3
((1S,4R)-4-(2-amino-6-chloro-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol
Codes: ABAC-007
Application context (from source-drug indications)
HIV infectionAbacavir Sulfate艾滋病痴呆综合征Abacavir Sulfate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Abacavir Sulfate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol→1,3-dimethyltetrahydropyrimidin-2(1H)-one→N-(4-(hydroxymethyl)cyclopent-2-en-1-yl)acetamide→4,6-dichloropyrimidin-2-amine→ABAC-003→4-chlorobenzenediazonium chloride→ABAC-005→ABAC-006→((1S,4R)-4-(2-amino-6-chloro-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol→cyclopropanamine
((1S,4R)-4-(2-amino-6-chloro-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol→(1R,5R)-5-(hydroxymethyl)cyclopent-2-enol→(3S,3aR,6aR)-3-hydroxy-3,3a,4,6a-tetrahydro-2H-cyclopenta[b]furan-2-one→(4aR,7aR)-4,4a,5,7a-tetrahydrocyclopenta[d][1,3]dioxin-2-one
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