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CAS 137054-45-6

4-methoxybenzyl 2-chloro-3,4-bis((4-methoxybenzyl)oxy)benzoate

CodesCEFID-003

Application context (from source-drug indications)

泌尿系统感染硫酸甲苯磺酸头孢德罗肾盂肾炎硫酸甲苯磺酸头孢德罗细菌感染硫酸甲苯磺酸头孢德罗呼吸机相关性肺炎硫酸甲苯磺酸头孢德罗细菌性肺炎硫酸甲苯磺酸头孢德罗医院获得性肺炎硫酸甲苯磺酸头孢德罗

Source drugs (routes using this intermediate)

DrugTierExpiry
硫酸甲苯磺酸头孢德罗Cefiderocol Sulfate TosylateTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

硫酸甲苯磺酸头孢德罗原研路线steps: 6total yield: 264 mg
2-chloro-3,4-dimethoxybenzoic acid2-chloro-3,4-dihydroxybenzoic acid4-methoxybenzyl 2-chloro-3,4-bis((4-methoxybenzyl)oxy)benzoate2-chloro-3,4-bis((4-methoxybenzyl)oxy)benzoic acid2-(pyrrolidin-1-yl)ethan-1-amine2-chloro-3,4-bis((4-methoxybenzyl)oxy)-N-(2-(pyrrolidin-1-yl)ethyl)benzamidetert-butyl 2-((((E)-1-(2-((tert-butoxycarbonyl)amino)thiazol-4-yl)-2-(((6R,7R)-2-(3,3-diphenylpropanoyl)-3-(iodomethyl)-5-oxido-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-7-yl)amino)-2-oxoethylidene)amino)oxy)-2-methylpropanoate1-(((6R,7R)-7-((E)-2-(((1-(tert-butoxy)-2-methyl-1-oxopropan-2-yl)oxy)imino)-2-(2-((tert-butoxycarbonyl)amino)thiazol-4-yl)acetamido)-2-(3,3-diphenylpropanoyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)-1-(2-(2-chloro-3,4-bis((4-methoxybenzyl)oxy)benzamido)ethyl)pyrrolidin-1-ium iodide

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