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CAS 13998-27-1

(2R,3R)-2,3-Dihydroxybutanedioic acid 3-[(1S)-1-hydroxy-2-(methylamino)ethyl]phenol

Codes:Phenylephrine Hydrochloride-036

Application context (from source-drug indications)

感冒布洛芬/盐酸去氧肾上腺素发热布洛芬/盐酸去氧肾上腺素头痛布洛芬/盐酸去氧肾上腺素

Source drugs (routes using this intermediate)

DrugTierExpiry
布洛芬/盐酸去氧肾上腺素Ibuprofen/Phenylephrine HydrochlorideTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

布洛芬/盐酸去氧肾上腺素优化路线steps: 6total yield: 108g(Phenylephrine Hydrochloride (API))
1-(3-Hydroxyphenyl)ethanone→2-Chloro-1-(3-hydroxyphenyl)ethan-1-one→Benzylmethylamine→1-(3-Hydroxyphenyl)-2-[methyl(phenylmethyl)amino]ethanone hydrochloride→3-[1-Hydroxy-2-(methylamino)ethyl]phenol→(2R,3R)-2,3-Dihydroxybutanedioic acid 3-[(1S)-1-hydroxy-2-(methylamino)ethyl]phenol→3-[(1R)-1-Hydroxy-2-(methylamino)ethyl]phenol

Intermediates available on this site

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