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CAS 140173-30-4
1-(4-Methoxyphenyl)-N-[1(R)-phenylethyl]propan-2(R)-amine
Codes：Tamsulosin Hydrochloride-040
Application context (from source-drug indications)
勃起功能障碍他达拉非/坦洛新前列腺增生他达拉非/坦洛新下尿路症状琥珀酸索利那新/盐酸坦洛新前列腺增生琥珀酸索利那新/盐酸坦洛新膀胱过度活动症琥珀酸索利那新/盐酸坦洛新药物相关的副作用和不良反应琥珀酸索利那新/盐酸坦洛新膀胱颈梗阻琥珀酸索利那新/盐酸坦洛新前列腺增生度他雄胺/盐酸坦洛新
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 他达拉非/坦洛新Tadalafil/Tamsulosin | Tier C — Watch / trade | - |
| 琥珀酸索利那新/盐酸坦洛新Solifenacin Succinate/Tamsulosin Hydrochloride | Tier C — Watch / trade | - |
| 度他雄胺/盐酸坦洛新Dutasteride/Tamsulosin Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-(4-Methoxyphenyl)-2-propanone→(R)-(-)-1-Phenylethylamine→1-(4-Methoxyphenyl)-N-[1(R)-phenylethyl]propan-2(R)-amine→5-[(2R)-2-aminopropyl]-2-methoxybenzene-1-sulfonic acid→1-(2-Bromoethoxy)-2-ethoxybenzene→5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzene-1-sulfonic acid→5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonyl chloride
1-(4-Methoxyphenyl)-2-propanone→(R)-(-)-1-Phenylethylamine→(2E)-1-(4-Methoxyphenyl)-N-[(1R)-1-phenylethyl]propan-2-imine→1-(4-Methoxyphenyl)-N-[1(R)-phenylethyl]propan-2(R)-amine→(-)-2-(4-Methoxyphenyl)-1-methylethanamine→(+/-)-tert-Butyl sulfinamide→(SR)-N-[(2E)-1-(4-Methoxyphenyl)propan-2-ylidene]-2-methylpropane-2-sulfinamide→(SR)-N-[(2R)-1-(4-Methoxyphenyl)propan-2-yl]-2-methylpropane-2-sulfinamide
1-(4-Methoxyphenyl)-2-propanone→(R)-(-)-1-Phenylethylamine→1-(4-Methoxyphenyl)-N-[1(R)-phenylethyl]propan-2(R)-amine→5-[(2R)-2-aminopropyl]-2-methoxybenzene-1-sulfonic acid→1-(2-Bromoethoxy)-2-ethoxybenzene→5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzene-1-sulfonic acid→5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonyl chloride
1-(4-Methoxyphenyl)-2-propanone→(R)-(-)-1-Phenylethylamine→(2E)-1-(4-Methoxyphenyl)-N-[(1R)-1-phenylethyl]propan-2-imine→1-(4-Methoxyphenyl)-N-[1(R)-phenylethyl]propan-2(R)-amine→(-)-2-(4-Methoxyphenyl)-1-methylethanamine→(+/-)-tert-Butyl sulfinamide→(SR)-N-[(2E)-1-(4-Methoxyphenyl)propan-2-ylidene]-2-methylpropane-2-sulfinamide→(SR)-N-[(2R)-1-(4-Methoxyphenyl)propan-2-yl]-2-methylpropane-2-sulfinamide
1-(4-Methoxyphenyl)-2-propanone→(R)-(-)-1-Phenylethylamine→1-(4-Methoxyphenyl)-N-[1(R)-phenylethyl]propan-2(R)-amine→5-[(2R)-2-aminopropyl]-2-methoxybenzene-1-sulfonic acid→1-(2-Bromoethoxy)-2-ethoxybenzene→5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzene-1-sulfonic acid→5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonyl chloride
1-(4-Methoxyphenyl)-2-propanone→(R)-(-)-1-Phenylethylamine→(2E)-1-(4-Methoxyphenyl)-N-[(1R)-1-phenylethyl]propan-2-imine→1-(4-Methoxyphenyl)-N-[1(R)-phenylethyl]propan-2(R)-amine→(-)-2-(4-Methoxyphenyl)-1-methylethanamine→(+/-)-tert-Butyl sulfinamide→(SR)-N-[(2E)-1-(4-Methoxyphenyl)propan-2-ylidene]-2-methylpropane-2-sulfinamide→(SR)-N-[(2R)-1-(4-Methoxyphenyl)propan-2-yl]-2-methylpropane-2-sulfinamide
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