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CAS 142355-81-5
tert-butyl 4-(4-bromobutyl)piperidine-1-carboxylate
Codes: TIRO-008
Application context (from source-drug indications)
Unstable anginaTirofiban Hydrochloride HydrateMyocardial infarctionTirofiban Hydrochloride HydrateCoronary thrombosisTirofiban Hydrochloride HydrateAcute coronary syndromeTirofiban Hydrochloride HydrateThrombosisTirofiban Hydrochloride HydrateCerebral infarctionTirofiban Hydrochloride Hydrate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Tirofiban Hydrochloride Hydrate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-(piperidin-4-yl)ethan-1-ol→tert-butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate→methyl 2-(triphenylphosphoranylidene)acetate→(E)-tert-butyl 4-(4-methoxy-4-oxobut-2-en-1-yl)piperidine-1-carboxylate→tert-butyl 4-(4-methoxy-4-oxobutyl)piperidine-1-carboxylate→4-(1-(tert-butoxycarbonyl)piperidin-4-yl)butanoic acid→tert-butyl 4-(4-hydroxybutyl)piperidine-1-carboxylate→tert-butyl 4-(4-bromobutyl)piperidine-1-carboxylate→(S)-2-(((benzyloxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoic acid→(S)-2-(((benzyloxy)carbonyl)amino)-3-(4-(4-(1-(tert-butoxycarbonyl)piperidin-4-yl)butoxy)phenyl)propanoic acid→(S)-tert-butyl 4-(4-(4-(2-(((benzyloxy)carbonyl)amino)-3-methoxy-3-oxopropyl)phenoxy)butyl)piperidine-1-carboxylate→(S)-tert-butyl 4-(4-(4-(2-amino-3-methoxy-3-oxopropyl)phenoxy)butyl)piperidine-1-carboxylate→butane-1-sulfonyl chloride→(S)-tert-butyl 4-(4-(4-(2-(butylsulfonamido)-3-methoxy-3-oxopropyl)phenoxy)butyl)piperidine-1-carboxylate
Intermediates available on this site
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