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CAS 1432591-86-0
(2S,3R,4S,5S,6R)-3,5-bis((tert-butyldiphenylsilyl)oxy)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-methyltetrahydro-2H-pyran-4-ol
Codes：DAPA-011
Application context (from source-drug indications)
二型糖尿病达格列净丙二醇/盐酸二甲双胍
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 达格列净丙二醇/盐酸二甲双胍Dapagliflozin Propanediol/Metformin Hydrochloride | Tier A — Act now | 2030 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(5-bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone→(1R,2S,3S,4R,5R)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol→(1R,2S,3S,4R,5R)-2,4-bis((tert-butyldiphenylsilyl)oxy)-6,8-dioxabicyclo[3.2.1]octan-3-ol→(2S,3R,4S,5S,6R)-3,5-bis((tert-butyldiphenylsilyl)oxy)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-methyltetrahydro-2H-pyran-4-ol
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