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CAS 1433399-02-0
(8S,13S,14S)-13-ethyl-3-methoxy-5',5'-dimethyl-6,7,8,12,13,14,15,16-octahydrospiro[cyclopenta[a]phenanthrene-17,2'-[1,3]dioxane]
Codes: ETON-022
Application context (from source-drug indications)
ContraceptionEtonogestrelAcquired immunodeficiency syndromeEtonogestrelDysmenorrhoeaEtonogestrel血崩EtonogestrelBenign prostatic hyperplasiaEtonogestrel月经失调Etonogestrel
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Etonogestrel | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(8S,9S,10R,13S,14S)-13-ethyl-11-methylene-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione→(13S,14S)-13-ethyl-3-methoxy-6,7,11,12,13,14,15,16-octahydro-17H-cyclopenta[a]phenanthren-17-one→(13S,14S)-13-ethyl-3-methoxy-6,7,8,12,13,14,15,16-octahydro-17H-cyclopenta[a]phenanthren-17-one→2,2-dimethylpropane-1,3-diol→(8S,13S,14S)-13-ethyl-3-methoxy-5',5'-dimethyl-6,7,8,12,13,14,15,16-octahydrospiro[cyclopenta[a]phenanthrene-17,2'-[1,3]dioxane]→(8S,9S,11R,13S,14S)-13-ethyl-3-methoxy-5',5'-dimethyl-6,7,8,9,11,12,13,14,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,2'-[1,3]dioxan]-11-ol→(8S,9S,13S,14S)-13-ethyl-3-methoxy-5',5'-dimethyl-6,8,9,12,13,14,15,16-octahydrospiro[cyclopenta[a]phenanthrene-17,2'-[1,3]dioxan]-11(7H)-one→(8S,9S,11S,13S,14S)-13-ethyl-3-methoxy-5',5'-dimethyl-11-((trimethylsilyl)methyl)-6,7,8,9,11,12,13,14,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,2'-[1,3]dioxan]-11-ol→(8S,9S,11S,13S,14S)-13-ethyl-3-methoxy-5',5'-dimethyl-11-((trimethylsilyl)methyl)-1,4,6,7,8,9,11,12,13,14,15,16-dodecahydrospiro[cyclopenta[a]phenanthrene-17,2'-[1,3]dioxan]-11-ol
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