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CAS 1450657-24-5
(R)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanol
Codes：APER-024
Application context (from source-drug indications)
斑块银屑病阿普米司特白塞病综合征阿普米司特口腔溃疡阿普米司特银屑病阿普米司特银屑病关节炎阿普米司特
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 阿普米司特Apremilast | Tier B — Position early | 2028 |
Position in synthesis routes (up/downstream chain)
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(2S)-2-acetamido-4-methylpentanoic acid→1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanone→(R)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanol→(S)-4-(1-azido-2-(methylsulfonyl)ethyl)-2-ethoxy-1-methoxybenzene→(S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine (S)-2-acetamido-4-methylpentanoate
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