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CAS 147404-76-0
methyl 1-((2'-carbamoyl-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate
Codes：AZIL-017
Application context (from source-drug indications)
高血压阿齐沙坦酯钾盐/氯噻酮原发性高血压阿齐沙坦酯钾盐/氯噻酮
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 阿齐沙坦酯钾盐/氯噻酮Azilsartan Medoxomil Potassium/Chlorthalidone | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
methyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate→methyl 2-ethoxy-1-((2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate→4'-methyl-[1,1'-biphenyl]-2-carboxamide→4'-(bromomethyl)-[1,1'-biphenyl]-2-carboxamide→methyl 2-((tert-butoxycarbonyl)((2'-carbamoyl-[1,1'-biphenyl]-4-yl)methyl)amino)-3-nitrobenzoate→methyl 2-(((2'-carbamoyl-[1,1'-biphenyl]-4-yl)methyl)amino)-3-nitrobenzoate→methyl 3-amino-2-(((2'-carbamoyl-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate→methyl 1-((2'-carbamoyl-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate→methyl 2-ethoxy-1-((2'-(ethoxy(imino)methyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate→2,6-dichloro-9-((3S,4R,5R)-3-fluoro-4-((triisopropylsilyl)oxy)-5-(((triisopropylsilyl)oxy)methyl)tetrahydrofuran-2-yl)-9H-purine
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