CAS 149353-96-8

4-(1-Acetylpiperidin-4-yl)benzoic acid

Codes: (XXII)859946-1-b

Application context (from source-drug indications)

Biliary tract cancerTasurgratinibBile duct cancerTasurgratinibSolid tumourTasurgratinibCholangiocarcinomaTasurgratinibBreast cancerTasurgratinibHepatic function declineTasurgratinib

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
Tasurgratinib	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

TasurgratinibOptimised routesteps: 4total yield: /

4-[1-(tert-Butoxycarbonyl)piperidin-4-yl]benzoic acid→4-Phenylpiperidine→1-(4-Phenylpiperidin-1-yl)ethan-1-one→4-(1-Acetylpiperidin-4-yl)benzoic acid→4-(Piperidin-4-yl)benzoic acid hydrogen chloride→N-Boc-4-(4-bromophenyl)piperidine

Intermediates available on this site

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