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CAS 151377-80-9
((3a'R,4S,6'S,6a'R)-2,2,2',2'-tetramethyldihydro-3a'H-spiro[[1,3]dioxolane-4,4'-furo[3,4-d][1,3]dioxol]-6'-yl)methanol
Codes：MIGA-027
Application context (from source-drug indications)
法布里病米加司他盐酸盐
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 米加司他盐酸盐Migalastat Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(3R,4R,5S)-2-(hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol→((3a'R,4S,6'S,6a'R)-2,2,2',2'-tetramethyldihydro-3a'H-spiro[[1,3]dioxolane-4,4'-furo[3,4-d][1,3]dioxol]-6'-yl)methanol→((3a'R,4S,6'S,6a'R)-2,2,2',2'-tetramethyldihydro-3a'H-spiro[[1,3]dioxolane-4,4'-furo[3,4-d][1,3]dioxol]-6'-yl)methyl trifluoromethanesulfonate→(3a'R,4S,6'S,6a'R)-6'-(azidomethyl)-2,2,2',2'-tetramethyldihydro-3a'H-spiro[[1,3]dioxolane-4,4'-furo[3,4-d][1,3]dioxole]→(2R,3R,4S,5S)-5-(azidomethyl)-2-(hydroxymethyl)tetrahydrofuran-2,3,4-triol
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