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CAS 152305-23-2
(S)-4-(4-aminobenzyl)oxazolidin-2-one
Codes: ZOLM-005
Application context (from source-drug indications)
MigraineZolmitriptan
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Zolmitriptan | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(S)-2-amino-3-(4-nitrophenyl)propanoic acid→methyl (S)-2-amino-3-(4-nitrophenyl)propanoate→(S)-2-amino-3-(4-nitrophenyl)propan-1-ol→(S)-4-(4-nitrobenzyl)oxazolidin-2-one→(S)-4-(4-aminobenzyl)oxazolidin-2-one→(S)-4-(4-hydrazinylbenzyl)oxazolidin-2-one→4-chloro-1,1-diethoxybutane→(S)-4-((3-(2-aminoethyl)-1H-indol-5-yl)methyl)oxazolidin-2-one
(S)-4-(4-aminobenzyl)oxazolidin-2-one→(S,E)-4-(4-(chlorodiazenyl)benzyl)oxazolidin-2-one→ethyl 2-acetyl-5-(1,3-dioxoisoindolin-2-yl)pentanoate→ethyl (S)-3-(2-(1,3-dioxoisoindolin-2-yl)ethyl)-5-((2-oxooxazolidin-4-yl)methyl)-1H-indole-2-carboxylate→ethyl (S)-3-(2-aminoethyl)-5-((2-oxooxazolidin-4-yl)methyl)-1H-indole-2-carboxylate hydrochloride→ethyl (S)-3-(2-aminoethyl)-5-((2-oxooxazolidin-4-yl)methyl)-1H-indole-2-carboxylate hydrochloride→ethyl (S)-3-(2-(dimethylamino)ethyl)-5-((2-oxooxazolidin-4-yl)methyl)-1H-indole-2-carboxylate
(S)-4-(4-aminobenzyl)oxazolidin-2-one→(S)-3-(2-(dimethylamino)ethyl)-5-((2-oxooxazolidin-4-yl)methyl)-1H-indole-2-carboxylic acid→4,4-diethoxy-N,N-dimethylbutan-1-amine
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