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CAS 1568179-08-7
(S)-3-amino-N,N-dimethylpyrrolidine-1-carboxamide
Codes: VORO-005
Application context (from source-drug indications)
Renal cell carcinomaVorolanibDiabetic macular oedemaVorolanib湿性年龄相关性黄斑变性VorolanibDiabetic retinopathyVorolanib肾肿瘤VorolanibHepatic function declineVorolanib
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Vorolanib | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
5-fluoroindolin-2-one→5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid→(Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid→3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl (Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylate→(S)-3-amino-N,N-dimethylpyrrolidine-1-carboxamide→(S,Z)-N-(1-(dimethylcarbamoyl)pyrrolidin-3-yl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
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