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CAS 159276-97-8

(6R,7R)-7-[[(2R)-2-Hydroxy-2-phenylacetyl]amino]-8-oxo-3-([[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl]methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid - N,N'-dibenzylethane-1,2-diamine

Codes: Cefonicid-018

Application context (from source-drug indications)

Bacterial infectionCefonicid Sodium

Source drugs (routes using this intermediate)

DrugTierExpiry
Cefonicid SodiumTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Cefonicid SodiumOriginator routesteps: 4total yield: /
(6R,7R)-3-(Acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid→Bis(sodium)bis[(5-sulfanyl-1H-tetrazol-1-yl)methanesulfonate]→(6R,7R)-7-Amino-8-oxo-3-([[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl]methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid→Formic acid 2-chloro-2-oxo-1(R)-phenylethyl ester<-fgf->O-Formyl-D-mandelic acid chloride<-fgf->D-O-Formylmandeolyl chloride→(6R,7R)-7-[[(2R)-2-Hydroxy-2-phenylacetyl]amino]-8-oxo-3-([[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl]methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid - N,N'-dibenzylethane-1,2-diamine

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